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Diabetes and Your Eyes
Diabetes can play havoc with your eyes, and sometimes there are
no early sumptoms. So you may have no idea anything is wrong
until your eyesight is in danger.
Here are the main eye problems that can be caused, or made
worse, by diabetes.
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Diabetes Awareness: The Downside....a New Wardrobe?
Here is some commonsense thinking: I can't understand why anyone who has diabetes wouldn't exercise and watch what they eat. The down side is that you may have to get an entire new wardrobe since exercise and healthy eating causes weight and size...
Diabetes, Impotence, and Viagra
25 Aug 2005
Approximately 8.7 million, or 8.7% of all men over the age of 20 in the United States have diabetes. The most life-threatening consequences of diabetes are heart disease and stroke, which strike people with diabetes more than twice...
Erectile dysfunction in diabetes
Question : I'M a diabetic, aged 46, and have been taking
anti-diabetic medication. During sexual intercourse, I have
difficulty in maintaining an erection.
Answer : MEN with diabetes have a higher risk of developing
erectile dysfunction...
General facts about Type II diabetes
Over 18 million Americans are suffering of type I diabetes or
type II diabetes. Other 4-5 million don't even know they have
the disease. It's a concerning 6% of the U.S. population.
Although it's not a fatal disease, diabetes is the sixth...
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Combination of Thiazide-Type Diuretic and Beta-Blocker may Cause Diabetes
Clinical Question: In patients with hypertension is it safe to combine thiazide-type diuretic and beta-blocker?
Bottom Line: Studies suggest that the routine combined use of a thiazide with a beta-blocker should be questioned in the early management of hypertension, particularly in patients who are at increased risk of developing new-onset diabetes. In such patients, the increased risk of developing diabetes may exceed the benefit of blood pressure lowering.
Reference: J Hypertens. 2005 Oct;23(10):1777-1781
Study Design: Retrieve randomized control trials and meta-analysis
Synopsis: Recently published trials addressing the pharmacological management of hypertension have reported an increase in new-onset diabetes mellitus when comparing certain older and newer treatment regimens. Thiazide-type diuretics (thiazides) and beta-blockers have been individually implicated, but these drugs are frequently combined, and the magnitude of risk associated with their combined use has not been quantified. So randomized control trials were retrieved that: (i) featured stepped treatment to manage hypertension; (ii) compared initial treatment using a thiazide or beta-blocker (older drug) with an angiotensin-converting enzyme inhibitor, angiotensin receptor blocker or calcium antagonist (newer drug); (iii) assessed cardiovascular outcomes; (iv) reported new-onset diabetes; and (v) provided at least 1-year follow-up. A meta-analysis of available trials indicated that patients exposed to treatment regimens combining thiazides and beta-blockers are at greater risk of developing diabetes than regimens avoiding this combination of drugs (risk ratio for alternative therapy 0.81, 95% confidence interval 0.77-0.86). Current data cannot inform reliably about the risks associated with individual older drugs because of similar overall exposures in patients starting on newer and older drugs.
About the Author
A Certified Family Physician of the Philippine Academy of Family Physician and continue to complete the requirements for Continuing Medical Education in Family Practice. Also a member of the Philippine Medical Informatics Society, Philippine Occupational Health and Safety Inc., and Pangasinan Medical Society.
Faculty Department of Physiology (Medicine) Lyseum- Northwestern University, Dagupan, Pangasinan, Faculty Medical Informatics Lyseu
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